helix-loop-helix

Fetched 2026-10-26 (cache).

Synonyms: helix loop helix

Antonyms: helix loop helix

Related words from Datamuse; suggestions, not definitions.

Noun

1. {{lb|en|biochemistry|genetics}} A [[w:structural motif|structural motif]] where two [[alpha helix|alpha helices]] are connected by a highly flexible [[amino acid]] loop, allowing the [[helix|helices]] to pack together. Usually requires forming a [[dimer]] with another HLH protein before binding [[deoxyribonucleic acid|DNA]].

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